Desi talks about following Meryl Streep on the show, coming to LA and getting a part in We Bought a Zoo with Matt Damon, her parents being conservative, working on “The Daily Show,” getting big news stories when she’s hosting, her online series “Desi Lydic Foxsplains,” and her new puppy accidentally getting high.

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Jimmy Kimmel serves as host and executive producer of Emmy® nominated “Jimmy Kimmel Live,” ABC’s late-night talk show. “Jimmy Kimmel Live” is well known for its viral video successes, with over 16 billion views and more than 19 million subscribers on the show’s YouTube channel. Some of Kimmel’s most popular comedy bits include Celebrities Read Mean Tweets, Lie Witness News, Halloween Candy YouTube Challenge, Jimmy and Cousin Sal pranking Aunt Chippy and music stars like Rihanna and Dua Lipa surprising Jimmy in the middle of the night.